Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20844923 | 0.86 | SMN1; SMN2 (0.42) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL20816262 | 0.85 | TSHR (0.50) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL20816242 | 0.81 | ADRB2 (0.39) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL20816243 | 0.81 | ADRB2 (0.39) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL20833378 | 0.81 | ADRB2 (0.39) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL4440600 | 0.80 | MAPT (0.47) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL2988614 | 0.80 | MAPT (0.47) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL2984081 | 0.80 | MAPT (0.47) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL20844916 | 0.77 | MAPT (0.39) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL9247642 | 0.76 | CA12 (0.68) | MAPTPDCD1CD274MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684773-B1 | THAILANSTATIN ANALOGS | PH PHARMA CO LTD (KR) | 2026-04-29 | — | — | EP | disclosed |
| CN-111788208-B | Talarstatin analogues | PH制药有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-12-31 | — | — | US | disclosed |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-12-31 | — | — | US | disclosed |
| US-10815246-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2020-10-27 | — | — | US | disclosed |
| US-10815246-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2020-10-27 | — | — | US | disclosed |
| EP-3684773-A1 | THAILANSTATIN ANALOGS | pH Pharma Co., Ltd. (KR) | 2020-07-29 | — | — | EP | disclosed |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| US-20190233430-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
| US-20190233430-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
| US-10301319-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2019-05-28 | — | — | US | disclosed |
| US-10301319-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2019-05-28 | — | — | US | disclosed |
| WO-2019060398-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019060398-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-28 | — | — | WO | disclosed |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-21 | — | — | US | disclosed |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190233430-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-10815246-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-10301319-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-11691982-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | MAPT 527/4885PDCD1 337/4885CD274 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.