⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20791175 | 1.00 | — | — | |
| SCHEMBL20791159 | 1.00 | — | — | |
| SCHEMBL20791161 | 1.00 | — | — | |
| SCHEMBL20791177 | 1.00 | — | — | |
| SCHEMBL20791157 | 1.00 | — | — | |
| SCHEMBL20238070 | 0.86 | GPR3 (0.31) | — | |
| SCHEMBL20238074 | 0.86 | GPR3 (0.31) | — | |
| SCHEMBL20238073 | 0.86 | GPR3 (0.31) | — | |
| SCHEMBL28740524 | 0.86 | GPR3 (0.31) | — | |
| SCHEMBL19614299 | 0.83 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-111601798-A | Bisamide sarcomere activating compound and use thereof | 美国安进公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-3681882-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | Amgen Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |