SCHEMBL20819953

SCHEMBL20819953

CCC[C@H]1CC[C@@H](C(=O)N(C)OC)N1C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22371763 1.00
SCHEMBL22388811 0.82
SCHEMBL29816933 0.79 HTR2C (0.45)
SCHEMBL28415781 0.79 HTR2C (0.45)
SCHEMBL28414275 0.79 HTR2C (0.45)
SCHEMBL22444297 0.78 FFAR2 (0.35)
SCHEMBL22371723 0.78 FFAR2 (0.35)
SCHEMBL20819885 0.78 FFAR2 (0.35)
SCHEMBL20819892 0.78 FFAR2 (0.35)
SCHEMBL28408623 0.78 FFAR2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681862-B1 BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2023-11-08 EP disclosed
US-20200277259-A1 BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2020-09-03 US disclosed
EP-3681862-A1 BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2020-07-22 EP disclosed
CN-111164072-A β -hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia 阿托基公司 2020-05-15 CN disclosed
WO-2019053425-A1 BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-03-21 WO disclosed