Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21279978 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL19085493 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL13363919 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL9160142 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL3729713 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL3729714 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL19480611 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL16315797 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL19681854 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ECES2CES1L3MBTL1 | |
| SCHEMBL24704614 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ECES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |