⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446835 | 0.69 | — | — | |
| SCHEMBL11484799 | 0.67 | — | — | |
| SCHEMBL20663274 | 0.67 | — | — | |
| SCHEMBL15801072 | 0.64 | — | — | |
| SCHEMBL13595856 | 0.54 | — | — | |
| SCHEMBL10446854 | 0.54 | — | — | |
| SCHEMBL248336 | 0.52 | ADH1B (0.60) | — | |
| SCHEMBL20825028 | 0.51 | — | — | |
| SCHEMBL16716399 | 0.50 | — | — | |
| SCHEMBL21696535 | 0.49 | SMN1; SMN2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |