Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15738439 | 1.00 | LMNA (0.71) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL12196470 | 0.94 | SMN1; SMN2 (0.76) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL15746977 | 0.90 | LMNA (0.70) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL24383295 | 0.90 | LMNA (0.63) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL13480435 | 0.90 | MAPT (0.65) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL13938297 | 0.90 | HTT (0.65) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL20288399 | 0.90 | LMNA (0.59) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL30316999 | 0.89 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL15679441 | 0.89 | MAPT (0.64) | LMNASMN1; SMN2MAPTIDO1HTT | |
| SCHEMBL13622021 | 0.89 | IDO1 (0.56) | LMNASMN1; SMN2MAPTIDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019052545-A1 | CYCLIC PEPTIDE ANTIBIOTICS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-21 | — | — | WO | disclosed |