Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414072 | 0.84 | ACE2 (0.52) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL20826003 | 0.83 | ACE2 (0.39) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL22552701 | 0.82 | GMNN (0.36) | BLMCYP1A2GMNNUSP2POLB | |
| SCHEMBL22552698 | 0.82 | GMNN (0.36) | BLMCYP1A2GMNNUSP2POLB | |
| SCHEMBL10906275 | 0.79 | MAPT (0.46) | ACE2LTA4HBLMCYP1A2USP2 | |
| SCHEMBL8694153 | 0.79 | LTA4H (0.50) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL8694155 | 0.79 | LTA4H (0.50) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL2470538 | 0.79 | LTA4H (0.50) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL1716727 | 0.79 | LTA4H (0.50) | ACE2LTA4HBLMCYP1A2GMNN | |
| SCHEMBL1716729 | 0.79 | LTA4H (0.50) | ACE2LTA4HBLMCYP1A2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019052545-A1 | CYCLIC PEPTIDE ANTIBIOTICS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-21 | — | — | WO | disclosed |