Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132275 | 1.00 | POLB (0.58) | POLBPLGHTR2AHTR6 | |
| SCHEMBL15667906 | 0.84 | NOS1 (0.49) | — | |
| SCHEMBL13738991 | 0.84 | NOS1 (0.49) | — | |
| SCHEMBL13738989 | 0.84 | NOS1 (0.49) | — | |
| SCHEMBL24222486 | 0.84 | POLB (0.58) | POLBHTR2AHTR6 | |
| SCHEMBL22456087 | 0.83 | POLB (0.51) | POLBHTR2AHTR6 | |
| SCHEMBL10132466 | 0.83 | POLB (0.51) | POLBHTR2AHTR6 | |
| SCHEMBL14940090 | 0.82 | POLB (0.60) | POLBHTR2AHTR6 | |
| SCHEMBL14940087 | 0.82 | POLB (0.60) | POLBHTR2AHTR6 | |
| SCHEMBL18994889 | 0.81 | CHRNB4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681862-B1 | BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3943491-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | Voronoi Inc. (KR) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190119-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | 주식회사 보로노이 | 2020-09-24 | — | — | WO | disclosed |
| WO-2019053425-A1 | BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2019-03-21 | — | — | WO | disclosed |