Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | FGF2 | P09038 | 1/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16476477 | 0.88 | CYP1A2 (0.58) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL12989785 | 0.85 | CYP1A2 (0.55) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL10424647 | 0.81 | CYP1A2 (0.83) | CYP1A2CYP46A1POLA1MEN1KMT2A | |
| SCHEMBL16330226 | 0.81 | POLA1 (0.71) | CYP1A2CYP46A1NR1H3POLA1NPC1 | |
| SCHEMBL26002941 | 0.80 | POLA1 (0.69) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL16476474 | 0.80 | CYP46A1 (0.67) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL19566728 | 0.80 | CYP46A1 (0.67) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL24473940 | 0.80 | CYP46A1 (0.68) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL19578615 | 0.80 | CYP46A1 (0.68) | CYP1A2FGF2CYP46A1NR1H3POLA1 | |
| SCHEMBL14964148 | 0.79 | CYP46A1 (0.70) | CYP1A2CYP46A1NR1H3POLA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205283-B1 | CHOLESTEROL CONJUGATES OF INHIBITORS OF VIRAL FUSION | MSD ITALIA SRL (IT) | 2019-03-20 | — | — | EP | disclosed |