Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512341 | 0.97 | SOAT1 (0.45) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| SCHEMBL23130129 | 0.94 | — | — | |
| SCHEMBL6218947 | 0.86 | — | — | |
| SCHEMBL7116355 | 0.82 | HSD17B10 (0.44) | TDP1PAOXHSD17B10 | |
| Methacrylic Acid SCHEMBL27494561 | 0.81 | TDP1 (0.48) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| Succinamide SCHEMBL1890528 | 0.79 | TDP1 (0.50) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| Urea SCHEMBL29201494 | 0.79 | CES1 (0.48) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| Ethylene SCHEMBL2344319 | 0.78 | KMT2A (0.44) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| Ethylene SCHEMBL15234457 | 0.78 | KMT2A (0.44) | TDP1KMT2ASOAT1TP53CYP1A2 | |
| SCHEMBL8466765 | 0.78 | TDP1 (0.41) | TDP1KMT2AMEN1PAOXALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507232-B1 | PROLINE DERIVATIVES | NATIONAL HEALTH RES INST (TW) | 2019-03-20 | — | — | EP | disclosed |