Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.30 |
| ▸ | PPARG | P37231 | 6/20 | 0.30 |
| ▸ | PPARD | Q03181 | 6/20 | 0.30 |
| ▸ | PPARA | Q07869 | 6/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
| ▸ | FABP4 | P15090 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797472 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL25978438 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL27605472 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL7116355 | 0.96 | HSD17B10 (0.44) | TDP1HSD17B10PAOXBTN3A1 | |
| SCHEMBL27383510 | 0.92 | HSD17B10 (0.41) | TDP1HSD17B10BTN3A1 | |
| SCHEMBL11399369 | 0.88 | — | — | |
| SCHEMBL22986932 | 0.87 | CES2 (0.50) | TDP1HSD17B10CES2CES1TSHR | |
| SCHEMBL3461175 | 0.87 | HSD17B10 (0.33) | TDP1HSD17B10 | |
| SCHEMBL466592 | 0.87 | GPR84 (0.43) | TDP1HSD17B10TSHRLMNAGPR84 | |
| SCHEMBL3188281 | 0.87 | CES2 (0.50) | TDP1HSD17B10CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118263-A1 | AGONISTS FOR TREATMENT OF EATING DISORDER | EMBARK BIOTECH APS (DK) | 2023-06-29 | — | — | WO | disclosed |
| EP-2934566-B1 | EXENDIN-4 DERIVATIVES AS DUAL GLP1/GIP OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS | SANOFI SA (FR) | 2017-06-21 | — | — | EP | disclosed |
| US-5872084-A | ESTERS OR THIOESTERS WITH POLYAMINES, AMIDAIO AD HYDROTREATMENT | EXXON CHEMICAL PATENTS, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0765349-B1 | LUBRICATING OIL DISPERSANTS DERIVED FROM HEAVY POLYAMINE | EXXON CHEMICAL PATENTS INC (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5756431-A | BASED ON CARBOXYL FUNCTIONALIZED HYDROCARBON | EXXON CHEMICAL PATENTS INC (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0765349-A1 | LUBRICATING OIL DISPERSANTS DERIVED FROM HEAVY POLYAMINE | EXXON CHEMICAL PATENTS INC. (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995035328-A1 | LUBRICATING OIL DISPERSANTS DERIVED FROM HEAVY POLYAMINE | EXXON CHEMICAL PATENTS INC. (US) | 1995-12-28 | — | — | WO | disclosed |