Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 12/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595614 | 0.98 | DNM1 (0.41) | DNM1KMT2ASMN1; SMN2KDM4AKDM4C | |
| SCHEMBL14586579 | 0.95 | DNM1 (0.36) | DNM1KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL23074571 | 0.93 | DNM1 (0.40) | DNM1KMT2ASMN1; SMN2KDM4AKDM4C | |
| SCHEMBL290461 | 0.86 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL13566363 | 0.85 | SMN1; SMN2 (0.36) | DNM1KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL16983769 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL6046844 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL379163 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL4960230 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL37833 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084929-A1 | CROSSLINKERS FOR MASS SPECTROMETRIC IDENTIFICATION AND QUANTITATION OF PEPTIDES | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084929-A1 | CROSSLINKERS FOR MASS SPECTROMETRIC IDENTIFICATION AND QUANTITATION OF PEPTIDES | PTMS, DCLRE1A, MTCL3 | DNM1 1168/4885KMT2A 4108/4885SMN1; SMN2 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.