SCHEMBL20829481

SCHEMBL20829481

Fc1ccc2c(c1F)CSc1c(cccc1-c1ccccc1)C2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.33
NOTUM Q6P988 1/20 0.32
ANPEP P15144 2/20 0.32
IL1RN P18510 1/20 0.32
ERAP2 Q6P179 1/20 0.32
ERAP1 Q9NZ08 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21183818 0.83 NOTUM (0.33) NOTUM
SCHEMBL21183807 0.79 CXCR5 (0.33)
SCHEMBL22261492 0.76 NOTUM (0.31) NOTUM
SCHEMBL19939944 0.75 RYR2 (0.32)
SCHEMBL22413717 0.71
SCHEMBL20015251 0.70 NOTUM (0.36) NOTUM
SCHEMBL20829466 0.69 PRCP (0.41) PRCPNOTUMANPEPIL1RNERAP2
SCHEMBL22270070 0.68 CA12 (0.32)
SCHEMBL28247140 0.65 MEN1 (0.50) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL27684703 0.65 ANPEP (0.50) PRCPANPEPIL1RNERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3686201-A1 INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2020-07-29 EP disclosed
WO-2019052565-A1 INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF 广东东阳光药业有限公司 2019-03-21 WO disclosed