SCHEMBL21183807

SCHEMBL21183807

Cc1cccc2c1SCc1c(ccc(F)c1F)C2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20123727 0.86 ACHE (0.35) MEN1KMT2A
SCHEMBL21183818 0.86 NOTUM (0.33)
SCHEMBL20123632 0.82 MEN1 (0.37) MEN1KMT2A
SCHEMBL20123649 0.80 ACHE (0.35) MEN1KMT2A
SCHEMBL20829481 0.79 PRCP (0.33)
SCHEMBL20123824 0.77 MEN1 (0.34) MEN1KMT2A
SCHEMBL20123682 0.77 ALDH1A1 (0.37) MEN1KMT2A
SCHEMBL19939944 0.75 RYR2 (0.32) MEN1KMT2A
SCHEMBL20014747 0.74 KMT2A (0.41) MEN1KMT2A
SCHEMBL20015251 0.73 NOTUM (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019144089-A1 CAP-DEPENDENT ENDONUCLEASE INHIBITORS TAIGEN BIOTECHNOLOGY CO., LTD. (TW) 2019-07-25 WO disclosed