Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16965398 | 0.87 | LCK (0.45) | MEN1KMT2ANQO2APAF1TDP2 | |
| SCHEMBL7186122 | 0.76 | MAPT (0.44) | MEN1KMT2ANQO2APAF1TDP2 | |
| SCHEMBL24715778 | 0.74 | NQO2 (0.39) | MEN1KMT2ANQO2GRM4NSD2 | |
| SCHEMBL16964932 | 0.72 | EGLN1 (0.44) | ALDH1A1MAPTHDAC8HTTHPGD | |
| SCHEMBL4699764 | 0.71 | PDE4A (0.62) | MEN1KMT2APDE4APDE4BPDE4C | |
| Ethane SCHEMBL27460273 | 0.70 | PDE4A (0.61) | MEN1KMT2APDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL4703616 | 0.70 | PDE4D (0.61) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL31331152 | 0.69 | NQO2 (0.55) | MEN1KMT2ANQO2GRM4NSD2 | |
| SCHEMBL2171704 | 0.69 | NQO2 (0.55) | MEN1KMT2ANQO2GRM4NSD2 | |
| SCHEMBL25291696 | 0.69 | KMT2A (0.49) | MEN1KMT2ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900239-B1 | DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, OCULAR DISEASES AND RELATED DISORDERS | WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2019-03-20 | — | — | EP | disclosed |