Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24715778 | 0.86 | NQO2 (0.39) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL25291696 | 0.80 | KMT2A (0.49) | MAPTMEN1KMT2AALDH1A1CASP3 | |
| SCHEMBL16965398 | 0.77 | LCK (0.45) | MAPTNQO2NSD2MEN1KMT2A | |
| SCHEMBL7177793 | 0.77 | NSD2 (0.41) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL7188128 | 0.77 | ALDH1A1 (0.42) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL20830484 | 0.76 | MEN1 (0.39) | MAPTNQO2NSD2MEN1KMT2A | |
| SCHEMBL31331152 | 0.76 | NQO2 (0.55) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL2171704 | 0.76 | NQO2 (0.55) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL4014412 | 0.74 | HTR1A (0.59) | MAPTNQO2HTR1AADRA1DADRA1A | |
| SCHEMBL3583657 | 0.74 | TGFBR1 (0.46) | NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583150-B1 | Cytotoxic propertie; antitumor; pyrido-(3,2-g)quinoline-5,10-diones; benzo(b)pyrido(4,3,2-de)(1,7)-phenanthroline-8-ones | LABORATORIE L. LAFON (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-1161432-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055160-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2000-09-21 | — | — | WO | disclosed |