⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469868 | 0.74 | — | — | |
| SCHEMBL211121 | 0.74 | — | — | |
| SCHEMBL211122 | 0.74 | — | — | |
| SCHEMBL28392894 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL243026 | 0.72 | — | — | |
| SCHEMBL5462458 | 0.70 | — | — | |
| SCHEMBL1259566 | 0.70 | — | — | |
| SCHEMBL3073132 | 0.70 | — | — | |
| SCHEMBL28949775 | 0.69 | EPHX2 (0.40) | — | |
| SCHEMBL967258 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113669-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
| US-8163756-B2 | For example,1-(3-t-butyl-1- (1,2,3,4-tetrahydro- isoquinolin-6-yl)-1H- pyrazol-5-yl)-3-(3- cyanophenyl)urea; for treatment of mammalian cancers and inflammatory diseases including rheumatoid arthritis, retinopathies | DECIPHERA PHARMACEUTICALS, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | disclosed |
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070078121-A1 | Enzyme modulators and treatments | DECIPHERA PHARMACEUTICALS, LLC | 2007-04-05 | — | — | US | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |
| CN-1536448-A | Single-layer electronic photographic photosensitive body | ���ǵ�����ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| US-20030072725-A1 | Topical cosmetic agents containing 2-hydrazino-1,3 -heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-04-17 | — | — | US | disclosed |
| EP-1259219-A2 | TOPICAL COSMETIC AGENTS CONTAINING 2-HYDRAZINO-1,3-HETEROAZOLES | HAARMANN & REIMER GMBH (DE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062208-A2 | TOPICAL COSMETIC AGENTS CONTAINING 2-HYDRAZINO-1,3-HETEROAZOLES | HAARMANN & REIMER GMBH (DE) | 2001-08-30 | — | — | WO | disclosed |
| EP-0652876-A1 | HERBICIDAL TRIAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003454-A1 | HERBICIDAL TRIAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |