⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859947 | 0.77 | — | — | |
| SCHEMBL3423116 | 0.72 | — | — | |
| SCHEMBL2083052 | 0.69 | — | — | |
| SCHEMBL28392894 | 0.69 | — | — | |
| SCHEMBL18469868 | 0.69 | — | — | |
| SCHEMBL211121 | 0.69 | — | — | |
| SCHEMBL211122 | 0.69 | — | — | |
| SCHEMBL27850617 | 0.69 | — | — | |
| SCHEMBL21136453 | 0.68 | — | — | |
| SCHEMBL21048220 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116634874-A | Fungicidal oxadiazoles and mixtures thereof | FMC公司 | 2023-08-22 | — | — | CN | claimed |
| CN-114262324-A | Bixazole drug molecule capable of being used for hospital nursing sterilization and application thereof | 河南科技大学第一附属医院 | 2022-04-01 | — | — | CN | claimed |
| US-11168086-B2 | Methods of synthesizing pyrazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2021-11-09 | — | — | US | claimed |
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | claimed |
| CN-104926801-B | Substituted azetidine analog derivative, the pharmaceutical composition containing it and its application in antitumor | 浙江大学 | 2019-06-04 | — | — | CN | claimed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-109476637-A | heterocyclic Prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2019-03-15 | — | — | CN | claimed |
| US-20180334461-A1 | NOVEL PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 2018-11-22 | — | — | US | claimed |
| US-10087149-B2 | Selective histone deacetylase 8 inhibitors | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-10-02 | — | — | US | claimed |
| CN-108368094-A | Non-steroidal glucocorticoid receptor modulators for topical drug delivery | 利奥制药有限公司 | 2018-08-03 | — | — | CN | claimed |
| US-20090286713-A9 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2009-11-19 | — | — | US | claimed |
| EP-1931706-A4 | COLLAGEN RECEPTOR I-DOMAIN BINDING MODULATORS | BIOTIE THERAPIES CORP (FI) | 2009-05-27 | — | — | EP | claimed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | claimed |
| US-20080255028-A1 | Collagen Receptor I-Domain Binding Modulators | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | claimed |
| EP-1931706-A1 | COLLAGEN RECEPTOR I-DOMAIN BINDING MODULATORS | Biotie Therapies Corp. (FI) | 2008-06-18 | — | — | EP | claimed |
| EP-1924554-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2008-05-28 | — | — | EP | claimed |
| WO-2007034035-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-29 | — | — | WO | claimed |
| WO-2007031608-A1 | COLLAGEN RECEPTOR I-DOMAIN BINDING MODULATORS | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-22 | — | — | WO | claimed |
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | claimed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | claimed |