Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2081456 | 0.98 | ALDH1A1 (0.44) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL25478967 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL1013681 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL4056715 | 0.83 | NPC1 (0.45) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL1264553 | 0.82 | CYP1A2 (0.61) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL1409752 | 0.82 | GRN (0.46) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL31265737 | 0.82 | GRN (0.46) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL1012342 | 0.82 | MAPK14 (0.50) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL31388010 | 0.82 | MAPK14 (0.48) | ALDH1A1GRNSORT1MAPK14MAPK11 | |
| SCHEMBL1012452 | 0.82 | MAPK14 (0.48) | ALDH1A1GRNSORT1MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796742-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-24 | — | — | US | disclosed |
| EP-2890460-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160340375-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| EP-2788348-B1 | KINASE INHIBITORS | CHIESI FARMA SPA (IT) | 2016-10-19 | — | — | EP | disclosed |
| EP-2788348-B1 | KINASE INHIBITORS | CHIESI FARMA SPA (IT) | 2016-10-19 | — | — | EP | disclosed |
| US-20150210722-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| EP-2890460-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| US-9029373-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-05-12 | — | — | US | disclosed |
| US-9029373-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-05-12 | — | — | US | disclosed |
| US-9029373-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-05-12 | — | — | US | disclosed |
| US-7202257-B2 | Anti-inflammatory medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202257-B2 | Anti-inflammatory medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-20070078121-A1 | Enzyme modulators and treatments | DECIPHERA PHARMACEUTICALS, LLC | 2007-04-05 | — | — | US | disclosed |
| US-20070037808-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-02-15 | — | — | US | disclosed |
| US-20070037808-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-02-15 | — | — | US | disclosed |
| US-20070037808-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-02-15 | — | — | US | disclosed |
| WO-2006081034-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006014290-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20050288286-A1 | Anti-inflammatory medicaments | DECIPHERA PHARMACEUTICALS, LLC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037808-A1 | p38 kinase inhibitors | MAPK1, MAP3K8, MAP3K1 | ALDH1A1 3608/4885GRN 2076/4885SORT1 4153/4885 |
| US-20050288286-A1 | Anti-inflammatory medicaments | MIF, PTGES2, TNF | ALDH1A1 3257/4885GRN 1341/4885SORT1 3809/4885 |
| US-20150210722-A1 | KINASE INHIBITORS | SYK, SRC, LYN | ALDH1A1 2702/4885GRN 3360/4885SORT1 3500/4885 |
| US-20160340375-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 2639/4885GRN 3218/4885SORT1 3481/4885 |
| US-20070078121-A1 | Enzyme modulators and treatments | ABL1, ABL2, LCK | ALDH1A1 1036/4885GRN 3968/4885SORT1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.