Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 17/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831430 | 1.00 | TRPC5 (0.70) | TRPC5KCNH2TRPC4ALDH1A1TIPARP | |
| SCHEMBL20831288 | 0.85 | TRPC5 (0.69) | TRPC5KCNH2TRPC4TIPARP | |
| SCHEMBL20818056 | 0.85 | TRPC5 (0.69) | TRPC5KCNH2TRPC4TIPARP | |
| SCHEMBL20818071 | 0.85 | TRPC5 (0.69) | TRPC5KCNH2TRPC4TIPARP | |
| SCHEMBL20831424 | 0.84 | TRPC5 (0.68) | TRPC5KCNH2TRPC4ALDH1A1 | |
| SCHEMBL20831486 | 0.83 | TRPC5 (1.00) | TRPC5KCNH2TRPC4ALDH1A1TIPARP | |
| SCHEMBL25686986 | 0.82 | TRPC5 (0.62) | TRPC5KCNH2TRPC4ALDH1A1TIPARP | |
| SCHEMBL20831566 | 0.80 | TRPC5 (0.84) | TRPC5KCNH2TRPC4ALDH1A1 | |
| SCHEMBL20818273 | 0.79 | TRPC5 (0.90) | TRPC5KCNH2TRPC4ALDH1A1TIPARP | |
| SCHEMBL20831427 | 0.79 | TRPC5 (0.54) | TRPC5KCNH2TRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |