Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 18/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818273 | 0.91 | TRPC5 (0.90) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20831739 | 0.86 | TRPC5 (0.73) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20831486 | 0.85 | TRPC5 (1.00) | TRPC5KCNH2TRPC4 | |
| SCHEMBL25701752 | 0.79 | TRPC5 (0.60) | TRPC5KCNH2TRPC4EPHX2GRIN2B | |
| SCHEMBL20831566 | 0.78 | TRPC5 (0.84) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20831429 | 0.77 | TRPC5 (0.89) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20818060 | 0.76 | TRPC5 (0.77) | TRPC5KCNH2TRPC4EPHX2 | |
| SCHEMBL20831448 | 0.76 | TRPC5 (0.82) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20832021 | 0.75 | TRPC5 (0.77) | TRPC5KCNH2TRPC4 | |
| SCHEMBL25687267 | 0.74 | TRPC5 (0.53) | TRPC5KCNH2TRPC4EPHX2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |