Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 6/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831758 | 1.00 | TRPC5 (0.38) | TRPC5HCRTR1HCRTR2TIPARPKCNH2 | |
| SCHEMBL20831245 | 1.00 | TRPC5 (0.38) | TRPC5HCRTR1HCRTR2TIPARPKCNH2 | |
| SCHEMBL20818320 | 0.91 | TRPC5 (0.40) | TRPC5TIPARPGPR119GRM2 | |
| SCHEMBL20818318 | 0.91 | TRPC5 (0.40) | TRPC5TIPARPGPR119GRM2 | |
| SCHEMBL20831944 | 0.91 | TRPC5 (0.40) | TRPC5TIPARPGPR119GRM2 | |
| SCHEMBL20831551 | 0.88 | TRPC5 (0.44) | TRPC5TIPARPKCNH2 | |
| SCHEMBL20831476 | 0.88 | TRPC5 (0.44) | TRPC5TIPARPKCNH2 | |
| SCHEMBL20831246 | 0.88 | TRPC5 (0.44) | TRPC5TIPARPKCNH2 | |
| SCHEMBL20831248 | 0.85 | TRPC5 (0.36) | TRPC5TIPARPKCNH2GPR119 | |
| SCHEMBL20831545 | 0.85 | TRPC5 (0.36) | TRPC5TIPARPKCNH2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |