Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818361 | 1.00 | TRPC5 (0.56) | TRPC5ALDH1A1GAAPOLBROCK2 | |
| SCHEMBL20831567 | 0.90 | TRPC5 (0.54) | TRPC5ALDH1A1ROCK2TRPC4 | |
| SCHEMBL20831563 | 0.90 | TRPC5 (0.54) | TRPC5ALDH1A1ROCK2TRPC4 | |
| SCHEMBL20831481 | 0.90 | TRPC5 (0.54) | TRPC5ALDH1A1GAATIPARPTRPC4 | |
| SCHEMBL20831651 | 0.89 | TRPC5 (0.59) | TRPC5ALDH1A1GAAPOLBROCK2 | |
| SCHEMBL20831648 | 0.89 | TRPC5 (0.59) | TRPC5ALDH1A1GAAPOLBROCK2 | |
| SCHEMBL20831643 | 0.86 | TRPC5 (0.55) | TRPC5ALDH1A1GAAPOLBROCK2 | |
| SCHEMBL20831565 | 0.86 | TRPC5 (0.55) | TRPC5ALDH1A1ROCK2TRPC4 | |
| SCHEMBL20831931 | 0.86 | TRPC5 (0.55) | TRPC5ALDH1A1GAAPOLBROCK2 | |
| SCHEMBL20831483 | 0.85 | TRPC5 (0.54) | TRPC5ALDH1A1POLBTIPARPTRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |