SCHEMBL20832018

SCHEMBL20832018

CCCOCCC(=O)NCC(=O)NC1C(O)CC(OP(=O)(O)OCC2OC(n3ccc(N)nc3=O)C(O)C2O)(C(=O)O)OC1C(O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CD22 P20273 8/20 0.43
ST6GAL1 P15907 6/20 0.42
P2RY2 P41231 3/20 0.41
P2RY4 P51582 2/20 0.40
P2RY6 Q15077 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18415627 1.00 CD22 (0.43) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL16645359 0.96 ST6GAL1 (0.44) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL20832121 0.95 ST6GAL1 (0.42) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL18073816 0.95 ST6GAL1 (0.42) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL18084276 0.92 ST6GAL1 (0.40) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL2605862 0.92 ST6GAL1 (0.40) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL10187590 0.92 ST6GAL1 (0.45) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL18494422 0.92 ST6GAL1 (0.47) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL18713167 0.91 ST6GAL1 (0.43) CD22ST6GAL1P2RY2P2RY4P2RY6
SCHEMBL17000271 0.91 ST6GAL1 (0.43) CD22ST6GAL1P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11135275-B2 Coagulation factor-targeting to TREM-like transcript 1 (TLT-1) on activated platelets NOVO NORDISK HEALTHCARE AG (CH) 2021-10-05 US disclosed
US-20190083587-A1 Coagulation factor-targeting to TLT-1 on activated platelets NOVO NORDISK AS (DK) 2019-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190083587-A1 Coagulation factor-targeting to TLT-1 on activated platelets TFPI, F13B, F3 CD22 1371/4885ST6GAL1 206/4885P2RY2 3043/4885
US-11135275-B2 Coagulation factor-targeting to TREM-like transcript 1 (TLT-1) on activated platelets TFPI, F3, F11 CD22 890/4885ST6GAL1 232/4885P2RY2 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.