Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833449 | 1.00 | KDM4E (0.39) | KDM4EMEN1TSHRKMT2AHPRT1 | |
| SCHEMBL22399679 | 0.80 | KDM4E (0.37) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL25605598 | 0.80 | KDM4E (0.37) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL22759957 | 0.80 | KDM4E (0.37) | KDM4EMEN1TSHRKMT2AHPRT1 | |
| SCHEMBL23487511 | 0.79 | MEN1 (0.46) | KDM4EMEN1TSHRKMT2ATK1 | |
| SCHEMBL22907647 | 0.79 | MEN1 (0.42) | KDM4EMEN1TSHRKMT2AHPRT1 | |
| SCHEMBL20833137 | 0.78 | — | — | |
| SCHEMBL21376542 | 0.77 | KDM4E (0.49) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL19146388 | 0.77 | KDM4E (0.49) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL24197308 | 0.77 | KDM4E (0.49) | KDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053659-A1 | MODIFIED NUCLEOSIDE PHOSPHORAMIDITES | ALIOS BIOPHARMA, INC. (US) | 2019-03-21 | — | — | WO | disclosed |