Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22065052 | 0.90 | BTN3A1 (0.38) | BTN3A1MAPK1SMN1; SMN2ALDH1A1MAPK14 | |
| SCHEMBL22066006 | 0.90 | BTN3A1 (0.38) | BTN3A1ALDH1A1MAPTELANECASP1 | |
| SCHEMBL22066004 | 0.90 | POLB (0.39) | BTN3A1SMN1; SMN2ALDH1A1MAPTCASP1 | |
| SCHEMBL22066002 | 0.90 | BTN3A1 (0.38) | BTN3A1MAPK1SMN1; SMN2ALDH1A1MAPK14 | |
| SCHEMBL22066288 | 0.89 | BTN3A1 (0.50) | BTN3A1MAPK1SMN1; SMN2ALDH1A1MAPK14 | |
| SCHEMBL22065039 | 0.88 | BTN3A1 (0.51) | BTN3A1ALDH1A1MAPTELANECASP1 | |
| SCHEMBL22065159 | 0.88 | BTN3A1 (0.45) | BTN3A1MAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15203143 | 0.86 | BTN3A1 (0.42) | BTN3A1SMN1; SMN2ALDH1A1MAPTELANE | |
| SCHEMBL24793363 | 0.85 | BTN3A1 (0.43) | BTN3A1MAPK1ALDH1A1MAPTELANE | |
| SCHEMBL22065044 | 0.85 | BTN3A1 (0.43) | BTN3A1SMN1; SMN2ALDH1A1MAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| WO-2019053476-A1 | FLOXURIDINE SYNTHESIS | NuCana plc (GB) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | BTN3A1 4531/4885MAPK1 2449/4885SMN1; SMN2 4594/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | BTN3A1 2948/4885MAPK1 3085/4885SMN1; SMN2 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.