Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423789 | 0.96 | PTPN1 (0.43) | TLR2HTR3AMEN1ALDH1A1MAPT | |
| SCHEMBL19423827 | 0.91 | PTPN1 (0.49) | HTR3AKMT2APTPN1 | |
| SCHEMBL19423826 | 0.86 | MEN1 (0.52) | HTR3AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19423787 | 0.82 | PTPN2 (0.50) | HTR3AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL20834029 | 0.81 | PTPN2 (0.49) | HTR3AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12221119 | 0.81 | TLR2 (0.42) | TLR2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL19423735 | 0.77 | TLR2 (0.59) | TLR2KMT2APTPN1 | |
| SCHEMBL20357069 | 0.77 | NPC1 (0.52) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL20370187 | 0.77 | NPC1 (0.52) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL17742665 | 0.76 | KMT2A (0.65) | HTR3AMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION | 2022-06-09 | — | — | US | disclosed |
| US-20190083574-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | LRBA, IAPP, FABP4 | TLR2 705/4885HTR3A 1838/4885MEN1 4132/4885 |
| US-20190083574-A1 | THERMOGENIC COMPOSITIONS AND METHODS | LRBA, IAPP, FABP4 | TLR2 705/4885HTR3A 1838/4885MEN1 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.