Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20834909 | 0.97 | MEN1 (0.31) | TYR | |
| SCHEMBL20834902 | 0.94 | FFAR1 (0.30) | — | |
| SCHEMBL23310015 | 0.84 | TYR (0.33) | TYR | |
| SCHEMBL23310012 | 0.82 | FFAR1 (0.31) | — | |
| SCHEMBL20834943 | 0.81 | TYR (0.32) | TYR | |
| SCHEMBL20834940 | 0.81 | MGLL (0.32) | — | |
| SCHEMBL23309988 | 0.81 | TYR (0.34) | TYR | |
| SCHEMBL20834870 | 0.80 | TYR (0.30) | TYR | |
| SCHEMBL20834944 | 0.78 | MEN1 (0.32) | TYR | |
| SCHEMBL23310001 | 0.77 | FFAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681976-B1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-20210122977-A1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-04-29 | — | — | US | disclosed |
| WO-2019052972-A1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-03-21 | — | — | WO | disclosed |