Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2081491 | 0.93 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL2083818 | 0.88 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL2081476 | 0.81 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL2083693 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL2082519 | 0.76 | MEN1 (0.34) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL2081494 | 0.75 | ALDH1A1 (0.33) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL7191945 | 0.72 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL2987452 | 0.71 | KDM4C (0.51) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL10679113 | 0.70 | KDM4C (0.53) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL772517 | 0.69 | KDM4C (0.50) | MEN1KMT2ANPC1RAB9AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897790-B2 | synthetic intermediate that is useful for efficient production of kahweofuran; flavoring; when thiophene compound is reacted in hydrogen atmosphere using transition metal catalyst, cyclization occurs simultaneously with reduction, to produce a 2,3-dihydrothieno[2,3c]furan skeleton in a single step | SAN-EI GEN F.F.I., INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | SAN EI GEN F.F.I., INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1854791-A1 | NOVEL THIOPHENE COMPOUND AND PROCESS FOR PRODUCING CAFFENOFURAN OR ANALOGUE THEREOF FROM THE SAME | SAN-EI GEN F.F.I., INC. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | CYP4F3, CBR3, GTF3C4 | MEN1 2693/4885KMT2A 1406/4885NPC1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.