Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067923 | 0.83 | TEAD4 (0.39) | TEAD4TRPM8MAPTALDH1A1POLB | |
| SCHEMBL17996069 | 0.78 | MEN1 (0.41) | TEAD4TRPM8MAPTALDH1A1POLB | |
| SCHEMBL920992 | 0.78 | TEAD4 (0.42) | TEAD4MAPTALDH1A1POLBTDP1 | |
| SCHEMBL10599245 | 0.74 | DPP4 (0.56) | DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL12508125 | 0.71 | DPP4 (0.50) | DPP4TRPM8MAPTALDH1A1MEN1 | |
| SCHEMBL509774 | 0.70 | NPC1 (0.33) | TEAD4MAPTALDH1A1POLBTDP1 | |
| SCHEMBL510274 | 0.70 | PPARG (0.40) | TEAD4TRPM8MAPTALDH1A1POLB | |
| SCHEMBL10154897 | 0.69 | DPP4 (0.51) | DPP4MAPTALDH1A1POLBMEN1 | |
| SCHEMBL13067606 | 0.68 | MAOA (0.38) | MAPTALDH1A1TDP1KMT2ANPBWR1 | |
| SCHEMBL20391368 | 0.66 | DPP4 (0.49) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059224-B1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |