SCHEMBL20837979

SCHEMBL20837979

c1cc2nc(c1)CNCCCNCCCNC2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 7/20 0.53
HTR2A P28223 2/20 0.37
ADRB1 P08588 1/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
CYP1A2 P05177 1/20 0.37
HTR1A P08908 1/20 0.37
CYP2D6 P10635 1/20 0.37
NCF1 P14598 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
HTR7 P34969 1/20 0.37
MTOR P42345 1/20 0.37
HTR3A P46098 1/20 0.37
HTR5A P47898 1/20 0.37
HTR6 P50406 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31649015 0.91 CXCR4 (0.53) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL8235408 0.91 CXCR4 (0.56) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL29520740 0.91 CXCR4 (0.56) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL1673295 0.91 CXCR4 (0.56) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL9207672 0.88 CXCR4 (0.58) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL13495066 0.83 CXCR4 (0.52) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL3094370 0.81 CXCR4 (0.53) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL3094376 0.81 CXCR4 (0.53) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL29418138 0.79 CXCR4 (0.51) CXCR4HTR2AADRB1HTR3EHTR3B
SCHEMBL14206482 0.78 CXCR4 (0.50) CXCR4HTR2AADRB1HTR2CSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190091673-A1 DISSOCIABLE NANOPARTICLES WITH INTER ALIA TRANSITION-METAL COMPLEX CATALYSTS OXFORD FINANCE LLC 2019-03-28 US disclosed