Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 5/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673295 | 1.00 | CXCR4 (0.56) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL29520740 | 1.00 | CXCR4 (0.56) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL9207672 | 0.97 | CXCR4 (0.58) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL20837979 | 0.91 | CXCR4 (0.53) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL29418138 | 0.88 | CXCR4 (0.51) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL13495066 | 0.87 | CXCR4 (0.52) | CXCR4ADRB1HTR2AHTR3EHTR3B | |
| SCHEMBL31649015 | 0.86 | CXCR4 (0.53) | CXCR4ADRB1HTR2AHTR3EHTR3B | |
| SCHEMBL14206482 | 0.82 | CXCR4 (0.50) | CXCR4APEX1ADRB1HTR2AHTR2C | |
| SCHEMBL8260287 | 0.82 | CXCR4 (0.43) | CXCR4APEX1TERTADRB1HTR2A | |
| SCHEMBL18312432 | 0.81 | CXCR4 (0.49) | CXCR4APEX1HTR2CKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210008031-A1 | SUPER-OXIDE DISMUTASE MIMETICS | KEREOS, INC. | 2021-01-14 | — | — | US | disclosed |
| US-20190328704-A1 | SUPER-OXIDE DISMUTASE MIMETICS | KEREOS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-10377783-B2 | Methods and compounds for enhancing contrast in magnetic resonance imaging (MRI) | BROCK UNIVERSITY (CA) | 2019-08-13 | — | — | US | disclosed |
| US-10350193-B2 | Super-oxide dismutase mimetics | GALERA LABS, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160362434-A1 | METHODS AND COMPOUNDS FOR ENHANCING CONTRAST IN MAGNETIC RESONANCE IMAGING (MRI) | BROCK UNIVERSITY (CA) | 2016-12-15 | — | — | US | disclosed |
| US-20160263085-A1 | SUPER-OXIDE DISMUTASE MIMETICS | KEREOS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-9353069-B2 | Super-oxide dismutase mimetics | GALERA LABS, LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-8486928-B2 | Super-oxide dismutase mimetics | GALERA THERAPEUTICS (US) | 2013-07-16 | — | — | US | disclosed |
| US-20100256178-A1 | SUPER-OXIDE DISMUTASE MIMETICS | GALERA LABS, LLC | 2010-10-07 | — | — | US | disclosed |
| US-20090131377-A1 | Combinations of Superoxide Dismutase Mimetics and Nonsteroidal Analgesic/Anti-Inflammatory Drugs | METAPHORE PHARMACEUTICALS, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-7445641-B1 | Biomaterials modified with superoxide dismutase mimics | PHARMACIA CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-20050171198-A1 | SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease | METAPHORE PHARMACEUTICALS, INC. | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171198-A1 | SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease | SOD1, MPO, SOD3 | CXCR4 1255/4885APEX1 1385/4885TERT 404/4885 |
| US-10377783-B2 | Methods and compounds for enhancing contrast in magnetic resonance imaging (MRI) | PPIP5K2, FABP7, MPI | CXCR4 2022/4885APEX1 3634/4885TERT 3794/4885 |
| US-20190328704-A1 | SUPER-OXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | CXCR4 4819/4885APEX1 110/4885TERT 669/4885 |
| US-10350193-B2 | Super-oxide dismutase mimetics | SOD1, SOD3, CAT | CXCR4 4812/4885APEX1 109/4885TERT 649/4885 |
| US-20100256178-A1 | SUPER-OXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | CXCR4 4812/4885APEX1 109/4885TERT 649/4885 |
| US-20090131377-A1 | Combinations of Superoxide Dismutase Mimetics and Nonsteroidal Analgesic/Anti-Inflammatory Drugs | SOD1, SOD3, CAT | CXCR4 3758/4885APEX1 849/4885TERT 3208/4885 |
| US-20160263085-A1 | SUPER-OXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | CXCR4 4812/4885APEX1 109/4885TERT 649/4885 |
| US-20160362434-A1 | METHODS AND COMPOUNDS FOR ENHANCING CONTRAST IN MAGNETIC RESONANCE IMAGING (MRI) | PPIP5K2, FABP7, MPI | CXCR4 2022/4885APEX1 3634/4885TERT 3794/4885 |
| US-20210008031-A1 | SUPER-OXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | CXCR4 4819/4885APEX1 110/4885TERT 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.