Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085200 | 0.79 | POLB (0.37) | — | |
| SCHEMBL2084414 | 0.76 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL3736376 | 0.74 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL3754756 | 0.68 | TNF (0.41) | CRHR1 | |
| SCHEMBL6312529 | 0.64 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL2082774 | 0.60 | KDM4E (0.38) | CRHR1 | |
| SCHEMBL6311936 | 0.60 | KMT2A (0.40) | — | |
| SCHEMBL6525042 | 0.60 | POLB (0.40) | — | |
| SCHEMBL2087037 | 0.59 | DAO (0.48) | — | |
| SCHEMBL9736099 | 0.58 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163935-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-24 | — | — | US | disclosed |