Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160826 | 0.81 | NPC1 (0.66) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL20838909 | 0.81 | ADORA1 (0.61) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL20838929 | 0.80 | HPGD (0.60) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL20838898 | 0.78 | ADORA1 (0.58) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL20838914 | 0.78 | ADORA1 (0.58) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL20838922 | 0.78 | ADORA1 (0.58) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL15715922 | 0.77 | ADORA1 (1.00) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL16338373 | 0.77 | CFTR (0.51) | KDM4EGAANPC1RAB9AALDH1A1 | |
| SCHEMBL20838918 | 0.75 | ADORA1 (0.57) | ADORA1KDM4EGAANPC1RAB9A | |
| SCHEMBL20838892 | 0.74 | ALDH1A1 (0.53) | ADORA1KDM4EGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759774-B2 | Inhibitors of hepatitis B virus targeting capsid assembly | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2020-09-01 | — | — | US | disclosed |
| US-10759774-B2 | Inhibitors of hepatitis B virus targeting capsid assembly | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190092742-A1 | INHIBITORS OF HEPATITIS B VIRUS TARGETING CAPSID ASSEMBLY | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-28 | — | — | US | disclosed |
| US-20190092742-A1 | INHIBITORS OF HEPATITIS B VIRUS TARGETING CAPSID ASSEMBLY | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092742-A1 | INHIBITORS OF HEPATITIS B VIRUS TARGETING CAPSID ASSEMBLY | HAVCR2, ZC3HAV1, HCCS | ADORA1 4438/4885KDM4E 3113/4885GAA 1119/4885 |
| US-10759774-B2 | Inhibitors of hepatitis B virus targeting capsid assembly | HAVCR2, ZC3HAV1, HCCS | ADORA1 4438/4885KDM4E 3113/4885GAA 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.