Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 16/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131181 | 0.88 | DHODH (1.00) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631366 | 0.88 | DHODH (1.00) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631444 | 0.87 | DHODH (0.77) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL30131122 | 0.86 | DHODH (0.80) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631490 | 0.86 | DHODH (0.80) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631451 | 0.86 | DHODH (1.00) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL30131171 | 0.86 | DHODH (1.00) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631459 | 0.86 | DHODH (0.84) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631419 | 0.85 | DHODH (0.80) | DHODHPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL19631467 | 0.85 | DHODH (1.00) | DHODHPOLBMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| EP-3459937-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | East China University of Science and Technology (CN) | 2019-03-27 | — | — | EP | disclosed |