Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631490 | 1.00 | DHODH (0.80) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631419 | 0.91 | DHODH (0.80) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30131181 | 0.89 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631366 | 0.89 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631451 | 0.87 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30131171 | 0.87 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL20956565 | 0.86 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631365 | 0.86 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL29911563 | 0.86 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL20842811 | 0.86 | DHODH (0.78) | DHODHKDM4EALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | FABP2, SLC10A2, ALPI | DHODH 803/4885KDM4E 4110/4885ALDH1A1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.