Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | CYCS | P99999 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843314 | 0.89 | SMN1; SMN2 (0.35) | ABCG2MAPTSMN1; SMN2TLR8TP53 | |
| SCHEMBL20843349 | 0.88 | TOP1 (0.52) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL2342864 | 0.88 | ABCG2 (0.56) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL2319612 | 0.88 | ABCG2 (0.56) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL2319605 | 0.88 | ABCG2 (0.56) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL2318530 | 0.88 | ABCG2 (0.56) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12893300 | 0.87 | ABCG2 (0.57) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL20843315 | 0.86 | TOP1 (0.53) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL13459435 | 0.85 | TOP1 (0.56) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12392084 | 0.84 | ABCG2 (0.47) | ABCG2TOP1CYCSMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459955-A1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | biolitec Unternehmensbeteiligungs II AG (AT) | 2019-03-27 | — | — | EP | disclosed |