Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.52 |
| ▸ | CYCS | P99999 | 3/20 | 0.51 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843315 | 0.94 | TOP1 (0.53) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL13459435 | 0.93 | TOP1 (0.56) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2310933 | 0.89 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2314588 | 0.89 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2314598 | 0.89 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL20843337 | 0.88 | ABCG2 (0.44) | TOP1CYCSMEN1MAPTKMT2A | |
| SCHEMBL20843311 | 0.84 | TOP1 (0.60) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL12451909 | 0.83 | TOP1 (0.58) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL12392113 | 0.83 | TOP1 (0.58) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL12392118 | 0.83 | TOP1 (0.52) | TOP1CYCSRARBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459955-A1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | biolitec Unternehmensbeteiligungs II AG (AT) | 2019-03-27 | — | — | EP | disclosed |