⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595437 | 0.85 | TSHR (0.35) | — | |
| SCHEMBL26427111 | 0.79 | CES2 (0.30) | — | |
| SCHEMBL27860677 | 0.74 | — | — | |
| SCHEMBL18394158 | 0.67 | — | — | |
| SCHEMBL5038224 | 0.67 | — | — | |
| SCHEMBL5038226 | 0.67 | — | — | |
| SCHEMBL3306355 | 0.67 | — | — | |
| SCHEMBL19604135 | 0.67 | — | — | |
| SCHEMBL32675940 | 0.67 | CES1 (0.35) | — | |
| SCHEMBL4368143 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019060862-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS VIA FAST-FLOW SYNTHESIS | SAREPTA THERAPEUTICS, INC. (US) | 2019-03-28 | — | — | WO | disclosed |