Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23349027 | 0.88 | FFAR1 (0.43) | FFAR1FFAR4PTGDR2SETDB1MRGPRX4 | |
| SCHEMBL30088417 | 0.86 | RXRA (0.48) | FFAR1FFAR4PTGDR2MRGPRX4KDM4E | |
| SCHEMBL20844673 | 0.86 | RXRA (0.48) | FFAR1FFAR4PTGDR2MRGPRX4KDM4E | |
| SCHEMBL28591388 | 0.85 | FFAR1 (0.42) | FFAR1FFAR4PTGDR2SETDB1MRGPRX4 | |
| SCHEMBL13199458 | 0.80 | CYP2A6 (0.48) | FFAR1FFAR4SETDB1KDM4EGAA | |
| SCHEMBL25087097 | 0.79 | SETDB1 (0.38) | FFAR1FFAR4PTGDR2SETDB1MRGPRX4 | |
| SCHEMBL20844672 | 0.79 | HTT (0.40) | FFAR1FFAR4PTGDR2SETDB1L3MBTL1 | |
| SCHEMBL5099691 | 0.79 | HSD17B10 (0.62) | FFAR1PTGDR2MRGPRX4GAAMAPT | |
| SCHEMBL25908752 | 0.79 | AKR1B1 (0.47) | FFAR1FFAR4PTGDR2KDM4EGAA | |
| SCHEMBL8436238 | 0.78 | CYP2A6 (0.41) | FFAR1FFAR4SETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057946-A1 | MULTI-CYCLIC AROMATIC COMPOUNDS AS FACTOR D INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-28 | — | — | WO | disclosed |