Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632624 | 0.78 | OPRL1 (0.59) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2677605 | 0.78 | OPRL1 (0.59) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4520767 | 0.77 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL14122218 | 0.77 | OPRM1 (0.42) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL14122215 | 0.77 | OPRM1 (0.42) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL6171130 | 0.77 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL1419783 | 0.77 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL2676517 | 0.77 | OPRM1 (0.55) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL2675785 | 0.77 | OPRM1 (0.55) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL378910 | 0.77 | OPRM1 (0.55) | OPRL1OPRM1OPRD1OPRK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057946-A1 | MULTI-CYCLIC AROMATIC COMPOUNDS AS FACTOR D INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-28 | — | — | WO | disclosed |