Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20844985 | 0.83 | HTT (0.35) | TP53MAPTRAB9AKMT2AGAA | |
| SCHEMBL20844979 | 0.81 | NR1H4 (0.33) | — | |
| SCHEMBL20844950 | 0.81 | — | — | |
| SCHEMBL20844904 | 0.77 | NR1H4 (0.33) | — | |
| SCHEMBL20844974 | 0.77 | KDM4E (0.36) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL20844994 | 0.77 | ALDH1A1 (0.30) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16439393 | 0.76 | MAPT (0.33) | TP53MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20844928 | 0.76 | CYP1A2 (0.31) | — | |
| SCHEMBL19909868 | 0.76 | ALDH1A1 (0.35) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL22564019 | 0.76 | NR1H4 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029038-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-03-27 | — | — | EP | disclosed |