Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ECE1 | P42892 | 4/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22800779 | 0.90 | KDM4E (0.60) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL13213432 | 0.90 | KDM4E (0.60) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL19487257 | 0.85 | KDM4E (0.58) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL22800683 | 0.85 | KDM4E (0.58) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL16750046 | 0.85 | ACE (0.70) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL13233530 | 0.85 | KDM4E (0.60) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL15592745 | 0.85 | ACE (0.70) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL19737124 | 0.85 | ACE (0.70) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL19386671 | 0.84 | KDM4E (0.56) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL24421008 | 0.84 | ACE (0.61) | KDM4EAPAF1POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019058367-A1 | LIPOPHILIC PEPTIDE PRODRUGS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-03-28 | — | — | WO | disclosed |