Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 6/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485620 | 0.84 | NNMT (0.52) | NNMTMEN1PABPC1KMT2AMAPT | |
| SCHEMBL17553321 | 0.83 | NNMT (0.45) | NNMTOXTRAVPR1ACRHR1MEN1 | |
| SCHEMBL16115684 | 0.79 | MEN1 (0.37) | NNMTOXTRAVPR1AMEN1PABPC1 | |
| SCHEMBL20845927 | 0.79 | NNMT (0.41) | NNMTMEN1KMT2AKDM4EGAA | |
| SCHEMBL31274754 | 0.78 | HPGD (0.39) | OXTRKDM4EMAPTAOC3HTT | |
| SCHEMBL19346801 | 0.78 | HPGD (0.39) | OXTRKDM4EMAPTAOC3HTT | |
| SCHEMBL15382533 | 0.78 | UHRF1 (0.45) | MEN1KMT2AKDM4EMAPTAOC3 | |
| SCHEMBL14840944 | 0.77 | NNMT (0.46) | NNMTOXTRMEN1PABPC1KMT2A | |
| SCHEMBL20845912 | 0.76 | NNMT (0.45) | NNMTOXTRCRHR1MEN1PABPC1 | |
| SCHEMBL16475219 | 0.76 | NNMT (0.49) | NNMTOXTRMEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978756-B1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES | Bayer Pharma AG (DE) | 2019-03-27 | — | — | EP | disclosed |