Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | DPYD | Q12882 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.34 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022430 | 0.73 | P2RY2 (0.46) | — | |
| SCHEMBL15803217 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL14791302 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL30287919 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL774016 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL64635 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL767777 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL21847661 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL10226283 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 | |
| SCHEMBL17329460 | 0.73 | PNP (0.44) | MAPTLMNATSHRPMP22SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | Lu, Qun (US) | 2023-06-01 | — | — | US | disclosed |
| US-20190091184-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER'S DISEASE | LU, QUN | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | CDC42, MDN1, GAP43 | GAA 3174/4885DPYD 2680/4885MAPT 267/4885 |
| US-20190091184-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER'S DISEASE | CDC42, MDN1, HASPIN | GAA 3203/4885DPYD 2616/4885MAPT 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.