Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145182 | 0.95 | ELANE (0.53) | ELANEKMT2AATMHSD17B10MAPT | |
| SCHEMBL18473065 | 0.88 | ELANE (0.42) | ELANEKMT2AATMFFAR1ACACB | |
| SCHEMBL691316 | 0.88 | ELANE (0.49) | ELANEKMT2AATMHSD17B10THRB | |
| SCHEMBL26362251 | 0.88 | MAOB (0.49) | ELANEKMT2AATMFFAR1HTT | |
| SCHEMBL22596640 | 0.88 | MAOB (0.49) | ELANEKMT2AATMFFAR1HTT | |
| SCHEMBL16140697 | 0.88 | ELANE (0.49) | ELANEKMT2AATMHSD17B10THRB | |
| SCHEMBL22596477 | 0.88 | MAOB (0.49) | ELANEKMT2AATMFFAR1HTT | |
| SCHEMBL26362357 | 0.85 | ELANE (0.53) | ELANEKMT2AATMHSD17B10THRB | |
| SCHEMBL26362231 | 0.85 | ELANE (0.53) | ELANEKMT2AATMHSD17B10THRB | |
| SCHEMBL10020927 | 0.85 | ELANE (0.47) | ELANEKMT2AATMHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725083-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-03-27 | — | — | EP | disclosed |