SCHEMBL691316

SCHEMBL691316

C=C(C)C(=O)OCc1ccc(-c2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.49
KMT2A Q03164 3/20 0.46
ATM Q13315 1/20 0.46
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HTR2A P28223 1/20 0.36
THRB P10828 1/20 0.36
FFAR1 O14842 1/20 0.36
TSHR P16473 1/20 0.36
MAOB P27338 4/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MAOA P21397 1/20 0.35
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16140697 1.00 ELANE (0.49) ELANEKMT2AATMPOLBAPEX1
SCHEMBL30420611 0.94 ELANE (0.55) ELANEKMT2AATMPOLBAPEX1
SCHEMBL10023763 0.91 ELANE (0.40) ELANEKMT2AATMPOLBAPEX1
SCHEMBL10020927 0.91 ELANE (0.47) ELANEKMT2AATMPOLBAPEX1
SCHEMBL24019226 0.90 ALDH1A1 (0.46) KMT2APOLBAPEX1HTTTDP1
SCHEMBL16125663 0.90 ALDH1A1 (0.46) KMT2APOLBAPEX1HTTTDP1
SCHEMBL22195195 0.90 ELANE (0.46) ELANEKMT2AATMPOLBAPEX1
SCHEMBL20664333 0.88 KMT2A (0.45) ELANEKMT2AATMPOLBAPEX1
SCHEMBL22600436 0.88 THRB (0.52) ELANEKMT2AATMPOLBAPEX1
SCHEMBL21475257 0.88 ELANE (0.46) ELANEKMT2AATMPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 829 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
US-20100309423-A1 Liquid Crystal Display MERCK PATENT GESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100309423-A1 Liquid Crystal Display MERCK PATENT GESELLSCHAFT (DE) 2010-12-09 US disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT (DE) 2010-10-28 US disclosed
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT (DE) 2010-10-28 US disclosed
EP-2243812-A2 Liquid crystal display Merck Patent GmbH (DE) 2010-10-27 EP disclosed
WO-2010089092-A1 LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
EP-2181173-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2010-05-05 EP disclosed
WO-2009030329-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2009030329-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY KLK3, BPHL, LPXN ELANE 402/4885KMT2A 4232/4885ATM 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.