Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901878 | 0.85 | POLB (0.36) | POLBCYP11B1CYP11B2AGBL2PTGS2 | |
| SCHEMBL17901809 | 0.84 | POLB (0.39) | POLBCYP11B1CYP11B2 | |
| SCHEMBL19755917 | 0.83 | POLB (0.37) | POLBCYP11B1CYP11B2AGBL2RORC | |
| SCHEMBL17901875 | 0.81 | POLB (0.39) | POLBAGBL2ALDH1A1KDM4EJAK2 | |
| SCHEMBL20847439 | 0.74 | POLB (0.40) | POLBACSS2 | |
| SCHEMBL19755916 | 0.74 | POLB (0.37) | POLBAGBL2ACSS2RORCPTGS2 | |
| SCHEMBL20847520 | 0.74 | POLB (0.38) | POLB | |
| SCHEMBL20847532 | 0.74 | POLB (0.38) | POLBALDH1A1PDE10A | |
| SCHEMBL20847336 | 0.73 | — | — | |
| SCHEMBL17896018 | 0.73 | POLB (0.39) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240786-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-27 | — | — | EP | disclosed |