Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19755915 | 0.89 | POLB (0.37) | POLBAGBL2JAK2JAK1TYK2 | |
| SCHEMBL20847335 | 0.84 | POLB (0.36) | POLB | |
| SCHEMBL17901811 | 0.82 | POLB (0.36) | POLB | |
| SCHEMBL20847445 | 0.81 | POLB (0.38) | POLBAGBL2JAK2JAK1TYK2 | |
| SCHEMBL17896030 | 0.80 | POLB (0.39) | POLBAGBL2 | |
| SCHEMBL20847336 | 0.79 | — | — | |
| SCHEMBL17895805 | 0.78 | POLB (0.36) | POLBAGBL2ALDH1A1 | |
| SCHEMBL17896023 | 0.77 | POLB (0.37) | POLBAGBL2ALDH1A1KMT2A | |
| SCHEMBL17009004 | 0.77 | POLB (0.37) | POLBKDM4EALDH1A1AGPAT2KMT2A | |
| SCHEMBL17901855 | 0.77 | POLB (0.33) | POLBAGBL2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107831-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2016-07-07 | — | — | WO | disclosed |