Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847615 | 0.86 | RORC (0.47) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847611 | 0.84 | HDAC6 (0.42) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847790 | 0.82 | RORC (0.53) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847470 | 0.78 | HDAC6 (0.50) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847721 | 0.76 | RORC (0.48) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847621 | 0.75 | USP2 (0.52) | HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847759 | 0.72 | HDAC6 (0.52) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL14842541 | 0.72 | RORC (0.62) | RORC | |
| SCHEMBL20847617 | 0.72 | HDAC6 (0.40) | RORCHDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL14842522 | 0.71 | RORC (0.61) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |